| Professor | |
| Name | Hou, Duen-Ren |
| Phone： | (03) 4227151 ext. 65981 |
| Professional field： Organic Chemistry |
|
| Research Interest | Development of various methodologies for organic synthesis, including new reactions, catalysis, asymmetry synthesis, and natural product synthesis. |
Diploma
| Country | School Name | Department | Degree |
|---|---|---|---|
Experience
| Duration |
|---|
| 2015.08 ~ 2018.07 |
| 2011.01 ~ Up to today |
| 2006.01 ~ 2011.01 |
| 2003.01 ~ 2006.01 |
| 2001.01 ~ 2003.01 |
| 2000.01 ~ 2001.01 |
| 1998.01 ~ 2000.01 |
Personal Honor
| Honor Category | Year | Award Name | Awarding Unit |
|---|---|---|---|
| Inside School Honor | 2011 |
Personal Research
Personal Journal
- Pin-Hsien Chen, Shu-Jung Hsu, Cheng-Chun Chen, Jui-Chen Fu, Duen-Ren Hou*. "Synthesis of Diarylamines via Nitrosonium-Initiated C-N Bond Formatio." Journal of Organic Chemistry, 2024, 89(14), 10316-10326.
- Pin-Hsien Chen, Shu-Jung Hsu, Duen-Ren Hou*. "Nitrosonium Ion Catalyzed Oxidative Bromination of Arenes" Advanced Synthesis & Catalysis, 2024, 366(7), 1575-1582.
- Chun-Wei Yeh, Chia-Chi Feng, Pei-Lin Chen, Yi-Jhen Jhou, and Duen-Ren Hou*. "Enantioselective Synthesis of Nabscessin C." The Journal of Organic Chemistry, 88(19), 2023, 13528-13534.
- Hung-Che Chen, Chi-Yun Liu, Venkatachalam Angamuthu, Wei-Chen Chen, Chi-Sheng Wen, Duen-Ren Hou*. "Synthesis of Optically Active Organofluorides by Ring Opening of Oxazolidinone-Fused Aziridines. " Org. Lett. 2023, 25(1), 190-194.
- Cheng-Chun Chen, Tzu-Hsuan Kuan, Wen-Wei Yuan, Shih-En Chen, Jui-Chen Fu, Yang-Xun Chen, Hui-Hsu Gavin Tsai,* and Duen-Ren Hou,*“Brønsted Acid-Promoted Benzannulation of o-Alkynylbenzaldehyde and Alkyne, and the Positive Effect of Propargyl Alcohol”2022, Advanced Synthesis & Catalysis, Volume: 364, Pages: 4122-4134.
- Thi Anh Hong Nguyen and Duen-Ren Hou*“Direct Acetoxylation of Arenes”2021, Organic Letters, Volume: 23, Issue: 21, Pages: 8127-8131.
- Tzu-Hsuan Kuan and Duen-Ren Hou*“Synthesis of 2‑Aryl Acetophenones via Hydrobromination and Oxyisomerization of (o‑Arylethynyl)benzyl Alcohols”2021, Journal of Organic Chemistry, Volume: 86, Issue: 9, Pages: 6907-6917.
- Chi-Yun Liu, Venkatachalam Angamuthu, Wei-Chen Chen, and Duen-Ren Hou*“Synthesis of Methyl L‑Kijanosides by Regio- and Stereoselective Ring Opening of 2‑Oxazolidinone-Fused Aziridines”2020, Organic Letters, Volume: 22, Issue: 6, Pages: 2246-2250.
- Hsin-Ying Wu, Wei-Yi Wang, Chia-Chi Feng, and Duen-Ren Hou*“Asymmetric Synthesis of Nabscessin A from Inositol and D‑Camphor”2020, Journal of Organic Chemistry, Volume: 85, Issue: 20, Pages: 13153-13159.
- Chi-Yun Liu, Venkatachalam Angamuthu, Wei-Chen Chen, and Duen-Ren Hou. "Synthesis of Methyl l-Kijanosides by Regio-and Stereoselective Ring Opening of 2-Oxazolidinone-Fused Aziridines. " Organic Letters, 2020, 22(6), 2246-2250.
- She-Hung Chan, Wohn-Jenn Leu, Sharada Prasanna Swain, Jui-Ling Hsu, Duen-Ren Hou, and Jih-Hwa Guh."Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells—Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy."International Journal of Molecular Sciences, 2020, 21(7), 2470.
- Le Thi Ngoc Chuc, Thi Anh Hong Nguyen and Duen-Ren Hou. "Acid–base-sensitive allylic oxidation of 2-allylbenzoic acids to form phthalides. "Organic & Biomolecular Chemistry, 2020 18(14), 2758-2768.
- Hsin-Ying Wu, Wei-Yi Wang, Chia-Chi FengChia-Chi Feng, Chia-Chi Feng, Duen-Ren Hou, "Asymmetric Synthesis of Nabscessin A from Inositol and d-Camphor. " The Journal of Organic Chemistry, 2020, 85(20), 13153-13159.
- Yi-Hua Sheng, Wohn-Jenn Leu, Ching-Nung Chen, Jui-Ling Hsu, Ying-Tung Liu, Lih-Ching Hsu, Duen-Ren Hou,Jih-Hwa Guh, "The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis." Molecules, 2020, 25(12), 2929.
- Ya-Ching Chang, Yu-Ling Tseng, Wohn-Jenn Leu, Chi-Min Du, Yi-Huei Jiang, Lih-Ching Hsu, Jui-Ling Hsu, Duen-Ren Hou, Jih-Hwa Guh, "Discovery of novel agents on spindle assembly checkpoint to sensitize vinorelbine-induced mitotic cell death against human non-small cell lung cancers." International journal of molecular sciences, 2020, 21(16), 5608.
- Yu‐Chun Wu, Yi Jhong, Hui‐Jie Lin, Sharada Prasanna Swain, Hui‐Hsu Gavin Tsai, Duen‐Ren Hou, "Organocatalyzed Enantioselective Michael Addition of 2‐Hydroxypyridines and α,β‐Unsaturated 1,4‐Dicarbonyl Compounds." Advanced Synthesis & Catalysis, 2019, 361(21), 4966-4982.
- Trimurtulu, Kotipalli and Duen-Ren Hou "Synthesis of 3-Bromoindenes from 4-Alkynyl Alcohols/Sulfonamides and Aldehydes via Prins Cyclization, Ring-Opening and Friedel-Crafts Reactions." Asian Journal of Organic Chemistry, 2019, 8(8), 1561-1571.
- Kotipalli, Trimurtulu, and Duen-Ren Hou "Synthesis of Indenes by a BF3· OEt2-Mediated, One-Pot Reaction of Aryl Homopropargyl Alcohols, Aldehydes, and Arenes." Organic letters, 2018, 20(16), 4787-4790.
- Agata Szymaszkiewicz, Marta Zielinska, Kun Li, Mani Ramanathan, Safiul Alam, Duen-Ren Hou, Jakub Fichna, Martin Storr "Novel derivatives of 1, 2, 3-triazole,cannabinoid-1 receptor ligands modulate gastrointestinal motility in mice." Naunyn-Schmiedeberg's archives of pharmacology, 2018, 391(4), 435-444.
- Venkatachalam Angamuthu, Wen-Jung Chang, Duen-Ren Hou. "Anti-addition of Dimethylsulfoxonium Methylide to Acyclic α, β-Unsaturated Ketones and Its Application in Formal Synthesis of an Eicosanoid." ACS Omega, 2017, 2(8), 4088-4099.
- Min-Ching Chung , Yung-Hsiang Chan , Wen-Jung Chang and Duen-Ren Hou. "Synthesis of 2, 3-dihydro-1 H-pyrroles by intramolecular cyclization of N-(3-butynyl)-sulfonamides." Organic & biomolecular chemistry, 2017, 15(17), 3783-3790.
- Le Thi Ngoc Chuc, Cheng-Sheng Chen, Wei-Shang Lo, Po-Chuan Shen, Yi-Chen Hsuan, Hui-Hsu Gavin Tsai, Fa-Kuen Shieh,
Duen-Ren Hou."Long-Range Olefin Isomerization Catalyzed by Palladium (0) Nanoparticles." ACS Omega, 2017, 2(2), 698-711. - Wohn-Jenn Leu, Sharada Prasanna Swain, She-Hung Chan, Jui-Ling Hsu, Shih-Ping Liu, Mei-Ling Chan, Chia-Chun Yu, Lih-Ching Hsu, Yen-Lin Chou, Wei-Ling Chang, Duen-Ren Hou, Jih-Hwa Guh. "Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways." Oncotarget, 2016, 7(47), 76995.
- Cheng‐Yu Chung, Venkatachalam Angamuthu, Long‐Shiang Li, Duen‐Ren Hou. "Palladium‐Catalyzed Allylic Substitution for the Synthesis of Pericosines." Asian Journal of Organic Chemistry, 2016, 5(11), 1327-1333.
- Ya-Jen Chang, Yi-Chen Hsuan, Alan Chuan-Ying Lai, Yun-Chiann Han, Duen-Ren Hou. "Synthesis of α-C-Galactosylceramide via Diastereoselective Aziridination: The New Immunostimulant 4′-epi-C-Glycoside of KRN7000." Organic letters, 2016, 18(4), 808-811.
- Ching-Nung Chen , Duen-Ren Hou. "Enantioselective synthesis of (+)-brevipolide H." Organic & biomolecular chemistry, 2016, 14(28), 6762-6768.
- Sharada Prasanna Swain, Yen‐Lin Chou, Duen‐Ren Hou. "Thioesterifications Free of Activating Agent and Thiol: A Three‐Component Reaction of Carboxylic Acids, Thioureas, and Michael Acceptors." Advanced Synthesis & Catalysis, 2015, 357(12), 2644-2650.